Heat a large skillet over medium-high heat.
Add ground beef to the skillet, breaking it into crumbles with a spatula.
Season beef with salt, black pepper, garlic powder, and onion powder.
Cook for 7-10 minutes, stirring occasionally, until beef is browned and cooked through.
Drain excess fat from the skillet if desired.
While beef is still hot, add shredded cheddar cheese and stir until melted. Remove from heat.
In a small bowl, whisk together mayonnaise, sugar-free ketchup, yellow mustard, pickle relish, apple cider vinegar, and paprika to create the special sauce.
Divide chopped romaine lettuce among four serving bowls.
Top each bowl with seasoned beef and melted cheese mixture.
Add cherry tomatoes, diced red onion, and pickle slices to each bowl.
Drizzle generously with special sauce.
Add optional toppings like bacon bits, avocado slices, or jalapeños if desired.
Serve immediately and enjoy your low-carb cheeseburger bowls.